GLAXO INC -- ALBUTEROL -- 6505-01-257-9953
===================== Product Identification ===================== Product ID:ALBUTEROL MSDS Date:11/12/1990 FSC:6505 NIIN:01-257-9953 === Responsible Party === Company Name:GLAXO INC Address:5 MOORE DR City:RESEARCH TRIANGLE PARK State:NC ZIP:27709 Country:US Info Phone Num:919-248-2354 Emergency Phone Num:919-248-2100/2700 CAGE:34006 === Contractor Identification === Company Name:GLAXO WELLCOME INC. Address:5 MOORE DR Box:13398 City:DURHAM State:NC ZIP:27709 Country:US Phone:919-248-2100 CAGE:34006 ============= Composition/Information on Ingredients ============= Ingred Name:ALBUTEROL CAS:18559-94-9 Fraction by Wt: 100% Other REC Limits:0.01 MG/M3 ===================== Hazards Identification ===================== Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO Health Hazards Acute and Chronic:ACUTE-EYE, SKIN & RESPIRATORY TRACT IRRITATION. ALBUTEROL IS A B2-ADRENEGIC BRONCHODILATOR AND MAY CAUSE MUSCULAR TREMOR,HEADACHE,NAUSEA,RAPID PULSE. CHRONIC-ELEVATED BLOOD PRESSURE AND EXACERBATION O F CARDIOVASCULAR DISEASES AND DIABETES. Explanation of Carcinogenicity:NONE OF THE COMPOUNDS IN THIS PRODUCT IS LISTED BY IARC, NTP, OR OSHA AS A CARCINOGEN. Effects of Overexposure:EYE, SKIN & RESPIRATORY TRACT IRRITATION, HEADACHE, NAUSEA, VOMITING, NERVOUSNESS, RAPID PULSE, INCREASES OR DECREASED BLOOD PRESSURE. Medical Cond Aggravated by Exposure:CARDIOVASCULAR AND DIABETES. ======================= First Aid Measures ======================= First Aid:INHALATION:REMOVE TO FRESH AIR. RESUSCITATE IF NOT BREATHING. GET MEDICAL ATTENTION. EYES:IMMEDIATELY FLUSH WITH PLENTY OF WATER FOR 15 MINUTES HOLDING EYELIDS OPEN. GET MEDICAL ATTENTION. SKIN:REMOVE CONTAMINATED CLOTHING. WASH WITH SOAP AND WATER. IF IRRITATION PERSISTS, GET MEDICAL ADVICE. INGESTION:DRINK LARGE AMOUNTS OF WATER, INDUCE VOMITING. GET IMMEDIATE MEDICAL ATTENTION. ===================== Fire Fighting Measures ===================== Extinguishing Media:USE WATER FOG, CARBON DIOXIDE, FOAM, OR DRY CHEMICAL. Fire Fighting Procedures:WEAR FIRE FIGHTING PROTECTIVE EQUIPMENT AND A FULL FACED SELF CONTAINED BREATHING APPARATUS. COOL FIRE EXPOSED CONTAINERS WITH WATER SPRAY. Unusual Fire/Explosion Hazard:COMBUSTION OR HEAT OF FIRE MAY PRODUCE HAZARDOUS DECOMPOSITION PRODUCTS AND VAPORS.AS WITH ANY ORGANIC DUST, THERE IS POTENTIAL FOR EXPLOSION WHEN SUSPENDED AIR ================== Accidental Release Measures ================== Spill Release Procedures:RECOVER BY VACUUMING. WASH RESIDUE WITH WATER. WEAR PROTECTIVE EQUIPMENT TO AVOID OVEREXPOSURE. Neutralizing Agent:NOT APPLICABLE. ====================== Handling and Storage ====================== Handling and Storage Precautions:STORE IN A COOL, DRY, WELL VENTILATED AREA. KEEP CONTAINERS TIGHTLY CLOSED WHEN NOT IN USE. PROTECT CONTAINERS FROM PHYSICAL DAMAGE. Other Precautions:DO NOT TAKE INTERNALLY. DO NOT BREATHE MIST/DUST UNLESS ADVISED BY A PHYSICIAN. AVOID PROLONGED OR REPEATED BREATHING OF VAPOR. AVOID CONTACT WITH EYES. USE WITH ADEQUATE VENTILATION. WASH THOROUGHLY AFTER HANDLING. ============= Exposure Controls/Personal Protection ============= Respiratory Protection:IF VENTILATION DOES NOT MAINTAIN INHALATION EXPOSURES BELOW PEL(TLV), USE NIOSH APPROVED ORGANIC VAPOR CARTRIDGE AND DUST/MIST PRE-FILTER RESPIRATORS AS PER CURRENT 29 CFR 1910.134, INSTRUCTIONS/WARNI NGS AND NIOSH-RESPIRATOR SELECTION. Ventilation:MECHANICAL (GENERAL) ROOM VENTILATION IS NORMALLY ADEQUATE. LOCAL EXHAUST MAY BE REQUIRED IF WORK AREA NOT VENTED. Protective Gloves:NEOPRENE, NITRILE, PVC OR NATURAL RUBBER Eye Protection:SAFETY GOGGLES. Other Protective Equipment:EYE WASH STATION. INDUSTRIAL-TYPE WORK CLOTHING AND APRON AS REQUIRED. Work Hygienic Practices:OBSERVE GOOD PERSONAL HYGIENE PRACTICES AND RECOMMENDED PROCEDURES. DO NOT WEAR CONTAMINATED CLOTHING OR FOOTWEAR. Supplemental Safety and Health AVOID PROLONGED OR REPEATED EXPOSURE. DO NOT GET ON SKIN OR IN EYES. DO NOT BREATHE VAPORS OR MISTS. ================== Physical/Chemical Properties ================== HCC:N1 Solubility in Water:1.5% Appearance and Odor:WHITE POWDER OR A SOLUTION, ODORLESS ================= Stability and Reactivity Data ================= Stability Indicator/Materials to Avoid:YES STRONG OXIDIZING AGENTS Stability Condition to Avoid:HIGH HEAT, OPEN FLAMES AND OTHER SOURCES OF IGNITION Hazardous Decomposition Products:CARBON MONOXIDE, CARBON DIOXIDE AND TOXIC OXIDES OF NITROGEN. ==================== Disposal Considerations ==================== Waste Disposal Methods:DISPOSAL SHOULD BE MADE IN ACCORDANCE WITH ALL APPLICABLE FEDERAL, STATE AND LOCAL LAWS AND REGULATIONS. PER MFR PRODUCT CAN BE INCINERATED AT AN APPROVED FACILITY. Disclaimer (provided with this information by the compiling agencies): This information is formulated for use by elements of the Department of Defense. The United States of America in no manner whatsoever, expressly or implied, warrants this information to be accurate and disclaims all liability for its use. Any person utilizing this document should seek competent professional advice to verify and assume responsibility for the suitability of this information to their particular situation.